🧠 Brain & Cognitive Enhancement

Angiotensin IV analog

• 10 million × more potent than BDNF at promoting synapse formation
• Enhances cognitive function and memory in studies
• Promotes neurogenesis (new brain cell growth)
• Research expanding in 2026 for neurodegenerative applications

🔥 Metabolic & Fat Loss

Mitochondrial-derived peptide

• AMPK activation pathway - the "exercise mimetic"
• Improved insulin sensitivity
• Often called "exercise in a bottle"
• Supports metabolic homeostasis

GHRH analog (Egrifta®)

• 8.3% visceral fat reduction over 12 months
• IGF-1 elevation without exogenous HGH
• Specifically targets belly fat
• Preserves subcutaneous fat distribution

Triple agonist (GIP/GLP-1/Glucagon)

• Up to 24% body weight loss in clinical trials
• Superior to semaglutide (Ozempic/Wegovy)
• Phase 3 trials completing 2026
• Expected FDA approval 2026-2027

AOD 9604

HGH Fragment (176-191)

• Fat burning benefits without IGF-1 elevation
• No blood sugar impact
• Same fat loss mechanism as full HGH
• Lower side effect profile

📖 Read more: AOD 9604: The Complete Evidence-Based Guide →

💪 Recovery & Repair

THE WOLVERINE COMPLEX

BPC-157 + TB-500 Synergistic Stack

Named after Marvel's regenerative mutant, this stack combines local tissue repair (BPC-157) with systemic healing (TB-500) for comprehensive recovery support.

Body Protection Compound

• Tendon & ligament healing acceleration
• Muscle injury recovery
• Angiogenesis promotion (new blood vessels)
• Nitric oxide modulation
• 100+ studies with no lethal dose ever found

📖 Complete Guide: BPC-157 Dosage, Benefits & Cycle Protocols →

TB-500

Thymosin Beta-4 Fragment

• Cell migration & systemic repair
• Tissue regeneration throughout body
• Anti-inflammatory properties
• Cardiac tissue support
• Actin regulation for cellular function

📚 Related Reading:

• What is Core Sleep? Maximize Recovery
• 7-Day High-Protein Meal Plan for Recovery
• High Protein Meal Prep Guide

🫁 Gut Health

Gastric pentadecapeptide

BPC-157 was originally isolated from gastric juice, making it uniquely suited for gut applications:

• IBD / Crohn's Disease - studied for inflammation reduction
• Ulcerative Colitis - mucosal healing support
• Leaky Gut Syndrome - tight junction repair
• NSAID-induced Damage - gastroprotective effects
• VEGF Upregulation - promotes healing blood vessel formation

📖 Why oral peptides fail: The Brutal Truth About Oral Peptides →

⚡ Hormonal & Libido

Vyleesi® - Melanocortin receptor agonist

• FDA approved for hypoactive sexual desire disorder
• Works for both men AND women
• Increases genuine desire, not just physical response
• Alternative when Viagra/Cialis ineffective

📖 Deep Dive: PT-141: The Brain-Based Solution for Sexual Performance →

KISSPEPTIN

GnRH Pulse Generator

• Stimulates natural LH/FSH production
• Testosterone support through natural pathways
• Reproductive health optimization
• Natural arousal enhancement

📖 Related: Does HIIT Training Increase Testosterone?

🛡️ Immune System

Zadaxin® - Immune modulator

• T-cell maturation and differentiation
• NK (Natural Killer) cell activation
• Dendritic cell signaling
• Used as cancer immunotherapy adjunct in multiple countries

LL-37

Human cathelicidin antimicrobial peptide

• Natural antimicrobial defense
• Biofilm disruption capabilities
• Wound healing acceleration
• Anti-viral properties

⏳ Anti-Aging & Longevity

Synthetic epithalamin tetrapeptide

• Telomerase activation - reactivates the enzyme that extends telomeres
• Telomere elongation support
• Melatonin regulation for sleep/circadian rhythm
• 33% lifespan increase in animal studies

GHK-Cu

Copper peptide complex

• Collagen synthesis stimulation
• Elastin production increase
• 4,000+ gene expression changes
• Hair follicle support
• Skin repair and regeneration

Mitochondrial-targeted peptide

• Mitochondrial function enhancement
• ATP production boost
• Oxidative stress reduction
• Heart failure trials ongoing in 2026

📈 Growth Hormone Optimization

💡 Popular 2026 Stack Protocol

CJC-1295 (no DAC) + Ipamorelin is the most popular GH secretagogue combination. The CJC provides sustained GHRH signaling while Ipamorelin triggers clean GH pulses without cortisol or prolactin spikes.

CJC-1295

Modified GHRH analog

• Extended half-life (8 days with DAC, ~30 min without)
• 2-10× IGF-1 increase
• Sustained GH elevation
• Once weekly dosing (with DAC) or daily (no DAC)

Selective GH secretagogue

• Clean GH pulse without side effects
• No cortisol or prolactin spike
• Excellent safety profile
• Synergistic with CJC-1295